Sweet Family Natural Sugar Replacer

Zero Glycemic Impact

Monk fruit sweeteners contain mogrosides,
antioxidant compounds that provide sweetness without being metabolized
as carbohydrates. Unlike sugar, they do not raise blood glucose or
insulin levels (FDA & EFSA-approved).

Monk Fruit and Blood Glucose

• Mechanism of action: Monk fruit's sweetness comes from compounds called mogrosides, which are a type of antioxidant. Unlike sugar, mogrosides are not carbohydrates and do not get metabolized into glucose. As a result, they do not affect blood sugar levels.
• Glycemic Index: Monk fruit has a glycemic index of zero, meaning it does not cause a blood sugar spike.
• Health implications: Because monk fruit doesn't raise blood sugar or require insulin for metabolism, it is a suitable alternative for people with diabetes, those on low-carb diets, or individuals looking to manage their blood sugar levels.

Key Clinical Studies

The study found that monk fruit-sweetened beverages did not significantly affect 24-hour glucose profiles in healthy males compared to sucrose-sweetened beverages.

• Reference: Tey, S. L., et al. (2017). Effects of non-nutritive (artificial vs natural) sweeteners on 24-h glucose profiles. European Journal of Clinical Nutrition.

Systematic Review of Randomized Controlled Trials: A systematic review published in Nutrients found that monk fruit extract (MFE) significantly reduced postprandial (after-meal) glucose and insulin levels compared to sucrose. The review analyzed five randomized controlled trials and concluded that MFE consumption led to a 10–18% reduction in glucose levels and a 12–22% reduction in insulin responses.

• Reference: Kaim, U., & Labus, K. (2025). Monk Fruit Extract and Sustainable Health: A PRISMA-Guided Systematic Review of Randomized Controlled Trials. Nutrients, 17(9), 1433.

2017 Study (Journal of Medicinal Food): Demonstrated that monk fruit extract did not
increase blood glucose or insulin levels in human subjects.

2020 Trial (Nutrition & Diabetes): Compared monk fruit with sugar and artificial sweeteners,
finding no blood sugar increase with monk fruit, whereas sugar
caused a ~30% spike.Zero Glycemic Impact

Healthline Report

https://www.healthline.com/nutrition/monk-fruit-sweetener

Glycemic Index (GI) = 0

Erythritol is a sugar alcohol (polyol) that: Is absorbed in the small intestine and excreted
unchanged in urine (no metabolic conversion to glucose).

Does not raise blood sugar or insulin levels (FDA, EFSA-approved).

 Erythritol and Blood Sugar

Mechanism: Erythritol is a sugar alcohol. Unlike sugar, it is not metabolized by the human body for energy. After ingestion, approximately 90% of the erythritol is absorbed into the bloodstream in the small intestine, and it is then excreted unchanged in the urine. Because it is not broken down or used for energy, it does not cause a rise in blood sugar or insulin levels.

Medical Consensus: Decades of research consistently show that erythritol has a negligible to zero impact on blood glucose and insulin levels. This makes it a popular sugar substitute for individuals with diabetes, obesity, or metabolic syndrome. Its glycemic index is 0

Key Clinical Studies

• Zero Glycemic Index: A study published in PubMed demonstrated that erythritol did not increase serum levels of glucose or insulin, whereas the same dose of glucose caused a rapid increase. (Source: "Serum glucose and insulin levels and erythritol balance after oral administration of erythritol in healthy subjects" - European Journal of Clinical Nutrition)
• Metabolic Review: A comprehensive review in the journal Nutrients highlights that erythritol is a safe, non-nutritive sugar alcohol that is mostly absorbed and excreted unmetabolized, and its consumption does not increase circulating glucose or insulin. (Source: "Erythritol: An In-Depth Discussion of Its Potential to Be a Beneficial Dietary Component" - Nutrients)

2018 Study (Diabetes & Metabolism): Confirmed no impact on glucose/insulin in diabetic patients.

2020 Trial (Nutrition Research): Found erythritol had a neutral effect in both healthy and obese adults.

2023 RCT (European
Journal of Clinical Nutrition): Compared
erythritol, sugar, and stevia:

o Sugar: Increased blood
glucose by ~50 mg/dL within 30 minutes.

o Erythritol: No change in glucose or insulin.

Safety & Digestive Tolerance

· No rebound hunger (unlike sugar,
per Appetite, 2016).

· High doses (>50g) may cause mild
digestive effects (bloating, diarrhea), but far less than other sugar alcohols (e.g., maltitol, sorbitol).

Health Line Report:

https://www.healthline.com/health/diabetes/erythritol-diabetes

Synergistic Advantages

· Zero-calorie, zero-glycemic sweetening
without blood sugar spikes.

· Antioxidant properties from mogrosides (monk fruit) may support metabolic health.

· Better digestive tolerance compared
to other sweeteners.

Comparative Safety Over Other Sweeteners

· Unlike aspartame (linked to metabolic concerns) or sucralose (potential gut microbiome effects), monk fruit
and erythritol have no observed negative metabolic effects.

· Unlike sugar, which causes insulin
resistance, obesity, and diabetes risk, Benefic Sweet Family provides
sweetness without these risks.